Clotting Factors
|
Name
|
Inheritance
|
t1/2
|
|
I
|
Fibrinogen
|
AR
|
2-4 days
|
|
II
|
Prothrombin
|
AR
|
3-4 days
|
|
III
|
Thromboplastin
|
AR
|
||
IV
|
Calcium
|
AR
|
||
V
|
Proaccelerin/Labile Factor
|
AR
|
36 hrs
|
|
VI
|
-
|
-
|
-
|
|
VII
|
Proconvertin/Stable Factor
|
AR
|
4-6 hrs
|
|
VIII
|
Anti-Hemophilic
Globulin/ Anti-Hemophilic Factor A
|
X-Linked
|
8-12 hrs
|
|
IX
|
Christmas Factor/ Anti-Hemophilic Factor B/ Plasma
Thromboplastic Component
|
X-linked
|
18-24 hrs
|
|
X
|
Stuart-Prower
Factor
|
AR
|
40-60 hrs
|
|
XI
|
Plasma
Thromboplastin Antecedent/
Anti-Hemophilic
Factor C
|
AR
|
40-70 hrs
|
|
XII
|
Hageman factor/
Glass Factor
|
AR
|
60 hrs
|
|
XIII
|
Fibrin Stabilizing Factor/ Laki Lorand Factor
|
AR
|
11-14 days
|
|
HMW-K
|
High Molecular Weight- Kininogen/
Fitzgerald Factor
|
AR
|
150 hrs
|
|
Prekallikrein
|
AR
|
35 hrs
|
||
Vit K Dependent Clotting factors:- (Vit K helps in gamma-carboxylation of the Glutamate residues of the following factors, which takes place in LIVER)
- Factor II
- Factor VII
- Factor IX
- Factor X
- Protein C
- Protein S
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